REG3A Protein (His tag)
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- Antigène Voir toutes REG3A Protéines
- REG3A (Regenerating Islet-Derived 3 alpha (REG3A))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette REG3A protéine est marqué à la His tag.
- Fonction
- Recombinant Human REG3A/HIP Protein (His Tag)
- Séquence
- Met 1-Asp 175
- Attributs du produit
- A DNA sequence encoding the human REG3A (Q06141-1) (Met 1-Asp 175) precursor was fused with a polyhistidine tag at the C-terminus.
- Pureté
- > 97 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product REG3A Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Antigène
- REG3A (Regenerating Islet-Derived 3 alpha (REG3A))
- Autre désignation
- REG3A/HIP (REG3A Produits)
- Synonymes
- HIP Protein, HIP/PAP Protein, INGAP Protein, PAP Protein, PAP-H Protein, PAP1 Protein, PBCGF Protein, REG-III Protein, REG3 Protein, AV063448 Protein, Pap2 Protein, PapII Protein, PTP Protein, REG3G Protein, regenerating family member 3 alpha Protein, regenerating islet-derived 3 alpha Protein, REG3A Protein, Reg3a Protein
- Sujet
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Background: Regenerating islet-derived protein 3-alpha, also known as Regenerating islet-derived protein III-alpha, REG-3-alpha, REG3A, and HIP, is secreted protein which contains one C-type lectin domain. REG3A is constitutively expressed in intestine, and is a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It is overexpressed during the acute phase of pancreatitis and in some patients with chronic pancreatitis. REG3A and REG1A proteins are both involved in liver and pancreatic regeneration and proliferation. REG3A is also a stress protein involved in the control of bacterial proliferation. REG3A is down-regulated in most primary human gastric cancer cells, and might be useful in the diagnosis of gastric cancer. Additionally, REG3A is a target of beta-catenin signaling in Huh7 hepatoma cells. The REG1A and REG3A are downstream targets of the Wnt pathway during liver tumorigenesis.
Synonym: HIP,HIP/PAP,INGAP,PAP,PAP-H,PAP1,PBCGF,REG-III,REG3,REG3A,REG3V
- Poids moléculaire
- 18 kDa
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