RNASET2 Protein (His tag)

N° du produit ABIN7197719

Détail du produit

Antigène: RNASET2 (Ribonuclease T2 (RNASET2))

Type de proteíne: Recombinant

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette RNASET2 protéine est marqué à la His tag.

Fonction: Recombinant Human RNASET2 Protein (Baculovirus, His Tag)

Séquence: Met 1-His 256

Attributs du produit: A DNA sequence encoding the human RNASET2 isoform 1 (O00584-1) (Met 1-His 256) was fused with a polyhistidine tag at the C-terminus.

Pureté: > 98 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: RNASET2 (Ribonuclease T2 (RNASET2))

Autre désignation: RNASET2 (RNASET2 Produits)

Synonymes: RNASE6PL Protein, bA514O12.3 Protein, MGC83874 Protein, MGC145364 Protein, dre2 Protein, wu:fc10c06 Protein, zgc:113369 Protein, ribonuclease T2 Protein, ribonuclease T2 L homeolog Protein, ribonuclease t2 Protein, RNASET2 Protein, Rnaset2 Protein, rnaset2.L Protein, rnaset2 Protein, TM1040_2631 Protein, RPE_1409 Protein, Bind_1696 Protein, Dd586_2225 Protein, Nhal_0810 Protein, Snov_2442 Protein, Fbal_2689 Protein, Nitsa_0808 Protein, Mesop_3495 Protein

Sujet:

Background: RNASET2 (ribonuclease T2) is an enzyme which belongs to the RNase T2 family. It is highly expressed in the temporal lobe and fetal brain. RNASET2 gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement. Defects in RNASET2 are the cause of leukoencephalopathy cystic without megalencephaly. An infantile-onset syndrome of cerebral leukoencephalopathy. Affected newborns develop microcephaly and neurologic abnormalities including psychomotor impairment, seizures and sensorineural hearing impairment. The brain shows multifocal white matter lesions, anterior temporal lobe subcortical cysts, pericystic abnormal myelination, ventriculomegaly and intracranial calcifications.

Synonym: Ribonuclease T2,3.1.27.-,Ribonuclease 6,RNASE6PL

Poids moléculaire: 28.5 kDa