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Stanniocalcin 1 Protein (STC1) (His tag)

STC1 Origine: Humain Hôte: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7319806
  • Antigène Voir toutes Stanniocalcin 1 (STC1) Protéines
    Stanniocalcin 1 (STC1)
    Type de proteíne
    Recombinant
    Origine
    • 6
    • 3
    • 3
    • 1
    Humain
    Source
    • 8
    • 2
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette Stanniocalcin 1 protéine est marqué à la His tag.
    Fonction
    Recombinant Human Stanniocalcin 1/STC-1 (C-6His)
    Séquence
    Thr18-Ala247
    Attributs du produit
    Recombinant Human Stanniocalcin 1 is produced by our Mammalian expression system and the target gene encoding Thr18-Ala247 is expressed with a 6His tag at the C-terminus.
    Pureté
    >95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product STC1 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène
    Stanniocalcin 1 (STC1)
    Autre désignation
    Stanniocalcin 1/STC-1 (STC1 Produits)
    Synonymes
    STC Protein, Stc Protein, stc1 Protein, MGC82280 Protein, STC1 Protein, zgc:153307 Protein, LOC777959 Protein, stanniocalcin 1 Protein, stanniocalcin 1 L homeolog Protein, stanniocalcin 1 S homeolog Protein, STC1 Protein, Stc1 Protein, stc1.L Protein, stc1.S Protein, stc1 Protein, LOC777959 Protein
    Sujet

    Background: Stanniocalcin 1 (STC-1) is a homodimeric glycoprotein hormone that is involved in calcium and phosphate homeostasis. It was originally identified in bony fishes, where elevation of calcium in serum causes the release of STC from the endocrine glands called the corpuscles of Stannius. STC-1 inhibits the breakdown of PAPP-A, protects cancer cells from apoptosis, reduces tumor size of liver cancers, promotes osteoblast differentiation and inhibits longitudinal bone growth directly at the growth plate. It is also a biomarker of brain and lung cancer progression. STC1 signals through inhibitory G-protein modulates CGRP receptor spatial localization during osteoblastogenesis and may function as a regulatory factor interacting with calcitonin peptide members during bone formation.

    Synonym: Stanniocalcin 1, stanniocalcin-1, STC1, STC-1, STCSTC-1

    Poids moléculaire
    26.9 kDa
    UniProt
    P52823
    Pathways
    Hormone Activity
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