Thymic Stromal Lymphopoietin Protein (TSLP) (His tag)
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- Antigène Voir toutes Thymic Stromal Lymphopoietin (TSLP) Protéines
- Thymic Stromal Lymphopoietin (TSLP)
- Type de proteíne
- Recombinant
- Activité biologique
- Active
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Origine
- Cynomolgus
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette Thymic Stromal Lymphopoietin protéine est marqué à la His tag.
- Fonction
- Recombinant Cynomolgus Thymic Stromal Lymphopoietin/TSLP (C-6His)
- Séquence
- Tyr29-Gln159(Glu37Gln)
- Attributs du produit
- Recombinant Cynomolgus Thymic Stromal Lymphopoietin is produced by our E.coli expression system and the target gene encoding Tyr29-Gln159(Glu37Gln) is expressed with a 6His tag at the C-terminus.
- Pureté
- >95 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Mouse TSLPR-Fc(Cat#PKSM041158) at 10μg/ml (100 μl/well) can bind Biotinylated Cynomolgus TSLP-His(Cat#PKSQ050102). The ED50 of Cynomolgus TSLP-His(Cat#PKSQ050102)is 3.2ug/ml .
- Top Product
- Discover our top product TSLP Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 500 mM NaCl, pH 7.4.
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Antigène
- Thymic Stromal Lymphopoietin (TSLP)
- Autre désignation
- Thymic Stromal Lymphopoietin/TSLP (TSLP Produits)
- Synonymes
- TSLP Protein, thymic stromal lymphopoietin Protein, TSLP Protein, Tslp Protein
- Sujet
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Background: Thymic stromal lymphopoietin (TSLP) is a protein belonging to the cytokine family, contains 140 amino acids. It is known to play an important role in the maturation of T cell populations through activation of antigen presenting cells. TSLP induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c+ dendritic cells. It can induce allergic inflammation by directly activating mast cells. TSLP is produced mainly by non-hematopoietic cells such as fibroblasts, epithelial cells and different types of stromal or stromal-like cells. These cells are located in regions where TSLP activity is required.
Synonym: Thymic stromal lymphopoietin, Thymic stroma-derived lymphopoietin, TSLP
- Poids moléculaire
- 16.2 kDa
- NCBI Accession
- XP_005557555
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