TPP1 Protein (His tag)
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- Antigène Voir toutes TPP1 Protéines
- TPP1 (Tripeptidyl Peptidase I (TPP1))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Human Cells
- Purification/Conjugué
- Cette TPP1 protéine est marqué à la His tag.
- Fonction
- Recombinant Human TPP1/CLN2 Protein (His Tag)
- Séquence
- Ser20-Pro563
- Attributs du produit
- Recombinant Human TPP1 is produced by our Mammalian expression system and the target gene encoding Ser20-Pro563 is expressed with a 6His tag at the C-terminus.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TPP1 Protéine
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mM GaCl2,10 % Glycerol, pH 7.5.
- Stock
- -20 °C
- Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Antigène
- TPP1 (Tripeptidyl Peptidase I (TPP1))
- Autre désignation
- TPP1/CLN2 (TPP1 Produits)
- Synonymes
- cln2 Protein, fa01b09 Protein, im:7149243 Protein, wu:fa01b09 Protein, CLN2 Protein, LPIC Protein, TPP-1 Protein, TPP-I Protein, Cln2 Protein, tripeptidyl peptidase I Protein, tripeptidyl-peptidase 1 Protein, tripeptidyl peptidase 1 Protein, tpp1 Protein, NAEGRDRAFT_78259 Protein, MCYG_00184 Protein, MGYG_05881 Protein, MGYG_00757 Protein, TPP1 Protein, Tpp1 Protein
- Sujet
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Background: Tripeptidyl-Peptidase 1 (TPP1) belongs to the peptidase S53 family. TPP1 is detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues. TPP1 is lysosomal serine protease with tripeptidyl-peptidase I activity. TPP1 may act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. TPP1 requires substrates with an unsubstituted N-terminus. TPP1 mutations have also been shown to cause neuronal ceroid lipofuscinosis type 2 (CLN2).
Synonym: Tripeptidyl-Peptidase 1, TPP-1, Cell Growth-Inhibiting Gene 1 Protein, Lysosomal Pepstatin-Insensitive Protease, LPIC, Tripeptidyl Aminopeptidase, TPP1, CLN2,GIG1,LPIC,SCAR7,TPP-1
- Poids moléculaire
- 60.35 kDa
- UniProt
- O14773
- Pathways
- Cycle Cellulaire, ER-Nucleus Signaling
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