UBE2V2 Protein (His tag)
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- Antigène Voir toutes UBE2V2 Protéines
- UBE2V2 (Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette UBE2V2 protéine est marqué à la His tag.
- Fonction
- Recombinant Human UBE2V2/DDVIT1 Protein (His Tag)
- Séquence
- Met 1-Asn145
- Attributs du produit
- Recombinant Human Ubiquitin-Conjugating Enzyme E2 Variant 2 is produced by our E.coli expression system and the target gene encoding Met1-Asn145 is expressed with a 6His tag at the N-terminus.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product UBE2V2 Protéine
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 50mm HEPES,150 mM NaCl, pH 7.0.
- Stock
- -20 °C
- Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Antigène
- UBE2V2 (Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2))
- Autre désignation
- UBE2V2/DDVIT1 (UBE2V2 Produits)
- Synonymes
- DDVIT1 Protein, DDVit-1 Protein, EDAF-1 Protein, EDPF-1 Protein, EDPF1 Protein, MMS2 Protein, UEV-2 Protein, UEV2 Protein, mms2 Protein, uev2 Protein, edpf1 Protein, uev-2 Protein, ddvit1 Protein, edaf-1 Protein, edpf-1 Protein, ddvit-1 Protein, 1110021H13Rik Protein, 4632410D19Rik Protein, 5730524P06Rik Protein, 6820402M05 Protein, AI848315 Protein, C81524 Protein, wu:fb18b11 Protein, wu:fb24d11 Protein, zgc:63717 Protein, UBE2V2 Protein, TMEM189-UBE2V1 Protein, ubiquitin conjugating enzyme E2 V2 Protein, ubiquitin-conjugating enzyme E2 variant 2 Protein, ubiquitin conjugating enzyme E2 V2 S homeolog Protein, Ubiquitin-conjugating enzyme E2 variant 2 Protein, UBE2V2 Protein, Ube2v2 Protein, ube2v2 Protein, ube2v2.S Protein, PTRG_00824 Protein, ub2v2 Protein, Tsp_08004 Protein
- Sujet
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Background: Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2) is an enzyme that belongs to the ubiquitin-conjugating enzyme family. UBE2V2 can be detected in the placenta, colon, liver, and skin. It forms a heterodimer with UBE2N. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains and which leads to protein degradation by the proteasome. UBE2V2 mediates transcriptional activation of target genes. It plays a role in the control of progress through the cell cycle and differentiation. It also plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
Synonym: Ubiquitin-Conjugating Enzyme E2 Variant 2, DDVit 1, Enterocyte Differentiation-Associated Factor 1, EDAF-1, Enterocyte Differentiation-Promoting Factor 1, EDPF-1, MMS2 Homolog, Vitamin D3-Inducible Protein, UBE2V2, MMS2, UEV2
- Poids moléculaire
- 18.5 kDa
- UniProt
- Q15819
- Pathways
- Positive Regulation of Response to DNA Damage Stimulus
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