UBE2G1 Protéine

N° du produit ABIN7198583

Détail du produit

Antigène: UBE2G1 (Ube2g1) (Ubiquitin-Conjugating Enzyme E2G 1 (Ube2g1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Fonction: Recombinant Human UBE2G1 Protein

Séquence: Met 1-Glu 170

Attributs du produit: A DNA sequence encoding the human UBE2G1 (P62253) (Met 1-Glu 170) was expressed and purified, with additional two amino acids (Gly & Pro) at the N-terminus.

Pureté: > 85 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, 10 % glycerol, pH 7.5

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: UBE2G1 (Ube2g1) (Ubiquitin-Conjugating Enzyme E2G 1 (Ube2g1))

Autre désignation: UBE2G1 (Ube2g1 Produits)

Synonymes: E217K Protein, UBC7 Protein, UBE2G Protein, 2700059C12Rik Protein, AI256795 Protein, AU014992 Protein, AW552068 Protein, D130023C12Rik Protein, Ubc7 Protein, e217k Protein, ubc7 Protein, ube2g Protein, UB2G1 Protein, ube2g1 Protein, ubiquitin conjugating enzyme E2 G1 Protein, ubiquitin-conjugating enzyme E2G 1 Protein, ubiquitin-conjugating enzyme E2 G1 Protein, ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) Protein, ubiquitin conjugating enzyme E2 G1 S homeolog Protein, UBE2G1 Protein, Ube2g1 Protein, EDI_082630 Protein, Bm1_26310 Protein, ube2g1 Protein, ube2g1.S Protein

Sujet:

Background: UBE2G1 is a member of the ubiquitin-conjugating E2 family whose members perform the second step in the ubiquitination reaction. Initially identified as the main process for protein degradation, ubiquitination is believed nowadays to be crucial for a wider range of cellular processes. The outcome of the ubiquitin-conjugation reaction, and thereby the fate of the substrate, is heavily dependent on the number of ubiquitin molecules attached and how these ubiquitin molecules are inter-connected. To deal with this complexity and to allow adequate ubiquitination in time and space, a highly sophisticated conjugation machinery has been developed. In a sequential manner, ubiquitin becomes activated by an ubiquitin-activating enzyme (E1), which then transfers the ubiquitin to a group of ubiquitin-conjugating enzymes (E2s). Next, ubiquitin-loaded E2s are interacting with ubiquitin protein ligases (E3s) and ubiquitin is conjugated to substrates on recruitment by the E3. These three key enzymes are operating in a hierarchical system, wherein two E1s and 35 E2s have been found and hundreds of E3s have been identified in humans. 

Synonym: E217K;UBC7;UBE2G

Poids moléculaire: 19.5 kDa

UniProt: P62253