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VISTA Protein (His tag)

VISTA Origine: Cynomolgus Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7320948
  • Antigène Voir toutes VISTA Protéines
    VISTA (V-type immunoglobulin domain-containing suppressor of T-cell activation (VISTA))
    Type de proteíne
    Recombinant
    Origine
    • 6
    • 1
    Cynomolgus
    Source
    • 2
    • 2
    • 2
    • 1
    Human Cells
    Purification/Conjugué
    Cette VISTA protéine est marqué à la His tag.
    Fonction
    Recombinant Cynomolgus VSIR Protein (His Tag)
    Séquence
    Phe33-Ala194
    Attributs du produit
    Recombinant Cynomolgus VSIR is produced by our Mammalian expression system and the target gene encoding Phe33-Ala194 is expressed with a 6His tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène
    VISTA (V-type immunoglobulin domain-containing suppressor of T-cell activation (VISTA))
    Autre désignation
    VSIR (VISTA Produits)
    Synonymes
    MGC112715 Protein, MGC151567 Protein, B7-H5 Protein, B7H5 Protein, GI24 Protein, PP2135 Protein, SISP1 Protein, Dies1 Protein, VISTA Protein, V-set immunoregulatory receptor Protein, vsir Protein, Vsir Protein, VSIR Protein
    Sujet

    Background: platelet receptor Gi24 is a single-pass type I membrane protein, and located at the cell surface. The protein can be cleaved by MMP14, and stimulate MMP14-mediated MMP2 activation. It is participated in the BMP signaling pathway. It also regulates the CD4-pasitive, alpha-beta T cell proliferation, and T cell cytokine production negatively. However, the protein can regulate stem cell differentiation positively.

    Synonym: Platelet receptor Gi24,Stress-induced secreted protein-1,Sisp-1,C10orf54,SISP1

    Poids moléculaire
    19.2 kDa
    UniProt
    A0A2K5UV12
    Pathways
    Cancer Immune Checkpoints
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