ZIKV E Protein (Fc Tag)
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- Antigène Tous les produits ZIKV E
- ZIKV E (Zika Virus Envelope (ZIKV E))
- Type de proteíne
- Recombinant
- Origine
- Zika Virus (ZIKV)
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette ZIKV E protéine est marqué à la Fc Tag.
- Fonction
- Recombinant ZIKV (strain Zika SPH2015) Envelope protein (Domain III, Fc Tag)
- Séquence
- Val593-Lys699
- Attributs du produit
- A DNA sequence encoding the Zika virus (strain Zika SPH2015) E / Envelope (domain III) (ALU33341.1) (Val593-Lys699) was expressed with the Fc region of human IgG1 at the C-terminus.
- Pureté
- > 90 % as determined by SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg protein as determined by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Antigène
- ZIKV E (Zika Virus Envelope (ZIKV E))
- Autre désignation
- Zika Envelope (ZIKV E Produits)
- Sujet
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Background: Envelope of Zika virus is resposible for receptor binding and membrane. Analysis of the envelope protein of Zika, from Brazilian Zika SPH215 (KU321639), indicates predicted B and T cell epitopes in peptides that are consistent to those reported for dengue, YFYF and Japanese encephalitis. The envelope Domain II B cell epitope, to which much dengue non-neutralizing cross reaction is attributed, is also conserved also in Zika virus, consistent with prior field observations of cross reactivity with dengue and YF. Domain III of the Zika envelope protein, likely the main specific neutralizing domain, is distinct from recent Brazilian dengue isolates and a recent Peruvian YF isolate (GQ379163), 76 % of possible major histocompatibility complex class (MHC) I and MHC II binding peptides and potential B cell linear epitopes are unique to Zika virus.
Synonym: Zika virus, E protein, strain Zika SPH2015
- Poids moléculaire
- 38.2kDa.
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