FGL1 Protein (His tag,Biotin)
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- Antigène Voir toutes FGL1 Protéines
- FGL1 (Fibrinogen-Like 1 (FGL1))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
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Origine
- Humain
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Source
- Human Cells
- Purification/Conjugué
- Cette FGL1 protéine est marqué à la His tag,Biotin.
- Fonction
- Recombinant Human FGL1 (C-Avi-6His) Biotinylated
- Séquence
- Leu23-Ile312
- Attributs du produit
- Biotinylated Recombinant Human Fibrinogen-like Protein 1 is produced by our Mammalian expression system and the target gene encoding Leu23-Ile312 is expressed with a Avi, 6His tag at the C-terminus.
- Pureté
- >90 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human LAG-3-Fc(Cat#CU30) at 10μg/ml (100 μl/well) can bind Biotinylated Human FGL1-Avi(Cat#CY21). The ED50 of Human FGL1-Avi (Cat#CY21) is 1908ng/mL.
- Top Product
- Discover our top product FGL1 Protéine
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- Commentaires
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35 kDa
- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 300 mM NaCl, 10 % Glycerol, 2 mM EDTA, pH 8.0.
- Stock
- -20 °C
- Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Antigène
- FGL1 (Fibrinogen-Like 1 (FGL1))
- Autre désignation
- FGL1 (FGL1 Produits)
- Synonymes
- MGC84748 Protein, FGL1 Protein, DKFZp470A2333 Protein, Frep1 Protein, Lfire1 Protein, HFREP1 Protein, HP-041 Protein, LFIRE-1 Protein, LFIRE1 Protein, Mfire1 Protein, fibrinogen like 1 L homeolog Protein, fibrinogen like 1 Protein, fibrinogen-like 1 Protein, fibrinogen-like protein 1 Protein, fgl1.L Protein, FGL1 Protein, Fgl1 Protein
- Sujet
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Background: Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3.
Synonym: Fibrinogen-like protein 1, FGL1, HP-041, Hepassocin, HFREP-1, LFIRE-1
- Poids moléculaire
- 36.6 kDa
- UniProt
- Q08830
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