Apolipoprotein C-II Protein (APOC2) (His tag)

N° du produit ABIN7318171

Détail du produit

Antigène: Apolipoprotein C-II (APOC2)

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Apolipoprotein C-II protéine est marqué à la His tag.

Fonction: Recombinant Human Apolipoprotein C-II/APOC2 Protein (His Tag)

Séquence: Met 1-Glu82

Attributs du produit: Recombinant Human Apolipoprotein C-II is produced by our E.coli expression system and the target gene encoding Met1-Glu82 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Commentaires:

14 kDa

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mMPB,150 mM NaCL,30 % glycerol, pH 7.2.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: Apolipoprotein C-II (APOC2)

Autre désignation: Apolipoprotein C-II (APOC2 Produits)

Synonymes: apoc2 Protein, apoC-II Protein, fb98g08 Protein, wu:fb52e03 Protein, wu:fb71a04 Protein, wu:fb98g08 Protein, APOC2 Protein, APO-CII Protein, APOC-II Protein, RGD1560725 Protein, APOCII Protein, Apo-CII Protein, ApoC-II Protein, apolipoprotein C-II Protein, apolipoprotein C2 Protein, apoc2 Protein, APOC2 Protein, Apoc2 Protein

Sujet:

Background: APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is also an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B) which characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis.

Synonym: Apolipoprotein C-II, Apolipoprotein C2, APC2 and APOC2

Poids moléculaire: 10.0 kDa

UniProt: P02655

Pathways: Lipid Metabolism