IgG1 Protein (Cys103Ser-Mutant, Leu117Phe-Mutant, Leu118Glu-Mutant, Pro214Ser-Mutant) (His tag)
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- Antigène Voir toutes IgG1 Protéines
- IgG1
- Type de proteíne
- Recombinant
- Attributs du protein
- Cys103Ser-Mutant, Leu117Phe-Mutant, Leu118Glu-Mutant, Pro214Ser-Mutant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette IgG1 protéine est marqué à la His tag.
- Fonction
- Human IgG1 Fc (C103S, L117F, L118E, P214S) Protein, His Tag
- Séquence
- Glu 99 - Lys 330
- Attributs du produit
- Human IgG1 Fc (C103S, L117F, L118E, P214S), His Tag (IG1-H52H9) is expressed from human 293 cells (HEK293). It contains AA Glu 99 - Lys 330 (Accession # P01857-1 (C103S, L117F, L118E, P214S).
- Pureté
- >95 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IgG1 Protéine
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- Indications d'application
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28 kDa. The protein migrates as 30-33 kDa under reducing (R) condition due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Stock
- -20 °C
- Stockage commentaire
- -20°C
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- Antigène
- IgG1
- Abstract
- IgG1 Produits
- Synonymes
- IgG1 Protein, Igh-4 Protein, VH7183 Protein, immunoglobulin heavy constant gamma 1 (G1m marker) Protein, Ighg1 Protein
- Classe de substances
- Antibody
- Sujet
- Synonyms:IgG1,Description:Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
- Poids moléculaire
- 28 kDa
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