IL17RC Protein (Fc-Avi Tag,Biotin)

N° du produit ABIN7273433

Détail du produit

Antigène: IL17RC (Interleukin 17 Receptor C (IL17RC))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette IL17RC protéine est marqué à la Fc-Avi Tag,Biotin.

Fonction: Biotinylated Human IL-17 RC Protein, Fc,Avitag™(MALS verified)

Séquence: Leu 21 - His 465

Attributs du produit: Biotinylated Human IL-17 RC, Fc,Avitag (ILC-H82F9) is expressed from human 293 cells (HEK293). It contains AA Leu 21 - His 465 (Accession # Q8NAC3-2).

Pureté: >95 % as determined by SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Classe de qualité: MALS verified

Information d'application

Indications d'application: This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 77.6 kDa. The protein migrates as 80-110 kDa under reducing (R) condition due to glycosylation.

Commentaires:

Ready-to-use Avitag™ biotinylated protein:
The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: IL17RC (Interleukin 17 Receptor C (IL17RC))

Autre désignation: IL-17 RC (IL17RC Produits)

Synonymes: IL17-RL Protein, IL17RL Protein, 1110025H02Rik Protein, Gm19850 Protein, IL-17RC Protein, IL17-RC Protein, Il17rl Protein, interleukin 17 receptor C Protein, Il17rc Protein, IL17RC Protein

Sujet: Synonyms:IL-17 RC,IL-17RC,IL17Rhom,IL-17 receptor C,IL-17RL,ZcytoR14,Description:Interleukin-17 receptor C (IL-17 RC), also known as IL17Rhom, IL-17RL, is the receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA. IL-17A activity is inhibited by IL-17RA, IL-17F is inhibited by IL-17RC, and a combination of soluble IL-17RA/IL-17RC receptors is required for inhibition of the IL-17F/IL-17A activity. Furthermore, activation of IL17RC can lead to the induction of expression of inflammatory chemokines and cytokines such as CXCL1.

Poids moléculaire: 77.6 kDa

NCBI Accession: NP_703190