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HLA-A*23:01 protein (SBP Tag)

Origine: Humain Hôte: Mammalian Cells Recombinant > 80 % BP, CP, ELISA, Neut
N° du produit ABIN7273165
  • Antigène
    HLA-A*23:01
    Type de proteíne
    Recombinant
    Origine
    Humain
    Source
    Mammalian Cells
    Purification/Conjugué
    SBP Tag
    Application
    Blocking Peptide (BP), Control Peptide (CP), ELISA, Neutralization (Neut)
    Fonction
    The product is HLA-A*23:01 complexed with β2-microglobulin (b2m)
    Séquence
    heavy chain: GSHSMRYFST SVSRPGRGEP RFIAVGYVDD TQFVRFDSDA ASQRMEPRAP WIEQEGPEYW DEETGKVKAH SQTDRENLRI ALRYYNQSEA GSHTLQMMFG CDVGSDGRFL RGYHQYAYDG KDYIALKEDL RSWTAADMAA QITQRKWEAA RVAEQLRAYL EGTCVDGLRR YLENGKETLQ RTDPPKTHMT HHPISDHEAT LRCWALGFYP AEITLTWQRD GEDQTQDTEL VETRPAGDGT FQKWAAVVVP SGEEQRYTCH VQHEGLPKPL TLRWEPSSQP TVHI
    light chain: IQRTPKIQVY SRHPAENGKS NFLNCYVSGF HPSDIEVDLL KNGERIEKVE HSDLSFSKDW SFYLLYYTEF TPTEKDEYAC RVNHVTLSQP KIVKWDRDM
    Sequences without tags. Tag location is at the discretion of the manufacturer.
    Specificité
    HLA-A*23:01 complexed with b2m, P04439 / P61769
    HLA-A23 is a split antigen of the HLA-A9 serotype. HLA-A*23:01 differs from HLA-A*24:02 only in four amino acid residues and is mainly found in Blacks.
    Attributs du produit
    HLAs are produced in mammalian cell cultures as recombinant, truncated, soluble antigens, in complex with β2-microglobulin (HLA class I). As part of our quality control, all HLA are analyzed for purity by gel electrophoresis, concentration is determined by ELISA (0.5 mg/ml) and their functionality is verified with a specific antiserum.
    Purification
    Chromatography
    Pureté
    > 80 %
    niveau d'endotoxine
    Endotoxins have not been removed
  • Indications d'application
    ELISA: 1 - 100 ng/mL
    Commentaires

    sandwich ELISA, direct ELISA, bead ELISA, reactive with antibodies W6/32 and BBM.1 and specific antiserum, B cell ELI Spot (predicted), in vitro memory B cell stimulation (predicted), HLA competition assay (predicted), control in various assays (predicted)

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    TRIS based buffer, pH 8.0, Sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Date de péremption
    6 months
  • Antigène
    HLA-A*23:01
    Sujet
    Human Leukozyte Antigen, human Antigen-presenting major histocompatibility complex class I (MHCI) molecule. Expressed on all cells, displays peptides to CD8-positive T cells. Involved in cellular immune response.
    Poids moléculaire
    approx. 50 kDa (38 kDa heavy chain + 12 kDa b2m)
    UniProt
    P04439
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