HLA-B*18:01 protein (SBP Tag)
Origine: Humain
Hôte: Mammalian Cells
Recombinant
> 80 %
BP, CP, ELISA, Neut
-
- Antigène
- HLA-B*18:01
- Type de proteíne
- Recombinant
- Origine
- Humain
- Source
- Mammalian Cells
- Purification/Conjugué
- SBP Tag
- Application
- Blocking Peptide (BP), Control Peptide (CP), ELISA, Neutralization (Neut)
- Fonction
- The product is HLA-B*18:01 complexed with β2-microglobulin (b2m)
- Séquence
-
heavy chain: GSHSMRYFYT AMSRPGRGEP RFISVGYVDD TQFVRFDSDA ASPREEPRAP WIEQEGPEYW DRNTQICKTN TQTYRESLRN LRGYYNQSEA GSHTLQRMYG CDVGPDGRLL RGHDQSAYDG KDYIALNEDL SSWTAADTAA QITQRKWEAA REAEQLRAYL EGLCVEWLRR YLENGKETLQ RADPPKTHVT HHPISDHEAT LRCWALGFYP AEITLTWQRD GEDQTQDTEL VETRPAGDRT FQKWAAVVVP SGEEQRYTCH VQHEGLPKPL TLRWEPSSQS TIPI
light chain: IQRTPKIQVY SRHPAENGKS NFLNCYVSGF HPSDIEVDLL KNGERIEKVE HSDLSFSKDW SFYLLYYTEF TPTEKDEYAC RVNHVTLSQP KIVKWDRDM
Sequences without tags. Tag location is at the discretion of the manufacturer. - Specificité
-
HLA-B*18:01 complexed with b2m, P01889 / P61769
HLA-B*B18:01 is most common in Nothern Italy and the Balkans with an average frequency of up to 17%. It reacts with anti-Bw6 antibodies. - Attributs du produit
- HLAs are produced in mammalian cell cultures as recombinant, truncated, soluble antigens, in complex with β2-microglobulin (HLA class I). As part of our quality control, all HLA are analyzed for purity by gel electrophoresis, concentration is determined by ELISA (0.5 mg/ml) and their functionality is verified with a specific antiserum.
- Purification
- Chromatography
- Pureté
- > 80 %
- niveau d'endotoxine
- Endotoxins have not been removed
-
- Indications d'application
- ELISA: 1 - 100 ng/mL
- Commentaires
-
sandwich ELISA, direct ELISA, bead ELISA, reactive with antibodies W6/32 and BBM.1 and specific antiserum, B cell ELI Spot (predicted), in vitro memory B cell stimulation (predicted), HLA competition assay (predicted), control in various assays (predicted)
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- TRIS based buffer, pH 8.0, Sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Date de péremption
- 6 months
-
- Antigène
- HLA-B*18:01
- Sujet
- Human Leukozyte Antigen, human Antigen-presenting major histocompatibility complex class I (MHCI) molecule. Expressed on all cells, displays peptides to CD8-positive T cells. Involved in cellular immune response.
- Poids moléculaire
- approx. 50 kDa (38 kDa heavy chain + 12 kDa b2m)
- UniProt
- P01889
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