S100A8/A9 Complex (Calprotectin) Protein (AA 1-93) (His tag)
Aperçu rapide pour S100A8/A9 Complex (Calprotectin) Protein (AA 1-93) (His tag) (ABIN7274018)
Antigène
Voir toutes S100A8/A9 Complex (Calprotectin) (S100A8/A9) ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Attributs du protein
- AA 1-93
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Purification/Conjugué
- Cette S100A8/A9 Complex (Calprotectin) protéine est marqué à la His tag.
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Fonction
- Human Calprotectin (S100A8&S100A9) Protein
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Séquence
- Met1-Glu93(S100A8) & Thr2-Pro114(S100A9)
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Attributs du produit
- Recombinant Human Calprotectin (S100A8&S100A9) Protein is expressed from E.coli with His tag at the C-Terminus of S100A8.It contains Met1-Glu93(S100A8) and Thr2-Pro114(S100A9).
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Stérilité
- 0.22 μm filtered
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niveau d'endotoxine
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Human Calprotectin (S100A8&S100A9) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.
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Buffer
- Lyophilized from 0.22μm filtered solution in 2 mM DTT, PBS ( pH 7.2). Normally 8 % trehalose is added as protectant before lyophilization.
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Agent conservateur
- Dithiothreitol (DTT)
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Précaution d'utilisation
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Date de péremption
- 12 months
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- S100A8/A9 Complex (Calprotectin) (S100A8/A9) (Calprotectin (S100A8/A9))
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Autre désignation
- Calprotectin
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Sujet
- Calprotectin, a member of the widespread calcium-binding S-100 protein family, is present in remarkably high concentration in the cytoplasm of human neutrophils. The calprotectin molecule is composed of light (MRP8) and heavy (MRP14) subunits. Although not secreted from intact neutrophils, calprotectin release from dead and dying neutrophils creates high concentrations of the protein in inflammatory or abscess fluids and in the intestinal tract lumen of patients with inflammatory bowel disease.
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Poids moléculaire
- 11.7 kDa (S100A8) and 13.2 kDa (S100A9) same as Bis-Tris PAGE result.
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UniProt
- P05109
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Pathways
- S100 Proteins
Antigène
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