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CD3 epsilon Protein (CD3E) (Fc Tag)

CD3E Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE
N° du produit ABIN7274301
  • Antigène Voir toutes CD3 epsilon (CD3E) Protéines
    CD3 epsilon (CD3E)
    Type de proteíne
    Recombinant
    Origine
    • 23
    • 9
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cynomolgus
    Source
    • 20
    • 8
    • 6
    • 5
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette CD3 epsilon protéine est marqué à la Fc Tag.
    Séquence
    Gln22-Asp117
    Pureté
    > 95% as determined by Tris-Bis PAGE
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Cynomolgus CD3E, hFc Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-CD3E Antibody, mFc Tag with the EC50 of 39.4ng/ml determined by ELISA. See testing image for detail.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    CD3 epsilon (CD3E)
    Autre désignation
    CD3E (CD3E Produits)
    Synonymes
    cd3e Protein, CD3E Protein, t3e Protein, tcre Protein, AI504783 Protein, CD3 Protein, CD3epsilon Protein, T3e Protein, T3E Protein, TCRE Protein, CD3e molecule Protein, CD3 antigen, epsilon polypeptide Protein, cd3e Protein, CD3E Protein, Cd3e Protein
    Sujet
    CD3e, CD3E, T3E, FLJ18683, TCRE, CD3-epsilon, IMD18,CD3E, is a single-pass type I membrane protein.CD3 (cluster of differentiation 3) T cell co-receptor helps to activate both the cytotoxic T cell (CD8 naive T cells) and also T helper cells (CD4 naive T cells). It consists of a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains.
    Poids moléculaire
    36.9 kDa. Due to glycosylation, the protein migrates to 43-48 kDa based on Tris-Bis PAGE result.
    Pathways
    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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