LI Cadherin Protein (AA 30-244) (His tag)
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- Antigène Voir toutes LI Cadherin Protéines
- LI Cadherin
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 30-244
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette LI Cadherin protéine est marqué à la His tag.
- Fonction
- Human CDH17/Cadherin 17 Domain 1 & 2 Protein
- Séquence
- Pro30-Pro244
- Attributs du produit
- Recombinant Human CDH17/Cadherin 17 Domain 1 & 2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Pro30-Pro244.
- Pureté
- > 95 % as determined by Tris-Bis PAGE
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human CDH17 Domain 1&2, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 11.4ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product LI Cadherin Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- LI Cadherin
- Autre désignation
- CDH17 (LI Cadherin Produits)
- Synonymes
- CDH16 Protein, HPT-1 Protein, HPT1 Protein, HPT-1/LI Protein, cb903 Protein, fb65d02 Protein, wu:fb65d02 Protein, cadherin-17 Protein, cadherin 17 Protein, cadherin 17, LI cadherin (liver-intestine) Protein, CDH17 Protein, Cdh17 Protein, cdh17 Protein
- Sujet
- Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
- Poids moléculaire
- 25.15 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Tris-Bis PAGE result.
- UniProt
- Q12864
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