PF4V1 Protein (AA 31-104) (Fc Tag)
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- Antigène Voir toutes PF4V1 Protéines
- PF4V1 (Platelet Factor 4 Variant 1 (PF4V1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 31-104
- Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette PF4V1 protéine est marqué à la Fc Tag.
- Fonction
- Human CXCL4L1 Protein
- Séquence
- Phe31-Ser104
- Attributs du produit
- Recombinant Human CXCL4L1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Phe31-Ser104.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- PF4V1 (Platelet Factor 4 Variant 1 (PF4V1))
- Autre désignation
- CXCL4L1 (PF4V1 Produits)
- Synonymes
- PF4A Protein, CXCL4L1 Protein, CXCL4V1 Protein, PF4-ALT Protein, SCYB4V1 Protein, PF4V1 Protein, platelet factor 4 variant 1 Protein, PF4V1 Protein
- Sujet
- Platelet factor-4 (CXCL4/PF-4) was the first chemokine shown to inhibit angiogenesis. CXCL4L1/PF-4var, recently isolated from thrombin-stimulated platelets, differing from authentic CXCL4/PF-4 in three carboxy-terminally located amino acids, was found to be more potent than CXCL4/PF-4 in inhibiting angiogenesis and tumor growth. Both glycosaminoglycans (GAG) and CXCR3 are implicated in the activities of the PF-4 variants.
- Poids moléculaire
- 35.01 kDa. Due to glycosylation, the protein migrates to 43-48 kDa based on Tris-Bis PAGE result.
- UniProt
- P10720
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