FCGR3B Protein (His-Avi Tag,Biotin)
-
- Antigène Voir toutes FCGR3B Protéines
- FCGR3B (Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B))
- Type de proteíne
- Recombinant
-
Origine
- Humain
-
Source
- HEK-293 Cells
- Purification/Conjugué
- Cette FCGR3B protéine est marqué à la His-Avi Tag,Biotin.
- Séquence
- Gly17-Ser200
- Pureté
- > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 4.3μM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product FCGR3B Protéine
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
-
- Antigène
- FCGR3B (Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B))
- Autre désignation
- Fc gamma RIIIB (FCGR3B Produits)
- Synonymes
- CD16 Protein, CD16b Protein, FCG3 Protein, FCGR3 Protein, FCR-10 Protein, FCRIII Protein, FCRIIIb Protein, FcRIII Protein, Fc fragment of IgG receptor IIIb Protein, Fc receptor, IgG, low affinity III Protein, Fc fragment of IgG receptor IIIa Protein, Fc-gamma RIII Protein, FCGR3B Protein, Fcgr3 Protein, FCGR3A Protein, FCGR3 Protein
- Sujet
- CD16, Fc gamma RIIIB, FCG3, Fc-gamma receptor IIIb (CD 16), Fc-gamma RIIIb, Fc-gamma RIII-beta, FCGR3B, FcgRIIIB, FCRIIIB, IGFR3, IgG Fc receptor III-1, CD16b (NA2), CD16B, FCG3B, FCG3, FCGR3, FCR-10,Human Fc gamma RIIIB/CD16b Protein is a receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
- Poids moléculaire
- 23.7 kDa. Due to glycosylation, the protein migrates to 47-53 kDa based on Tris-Bis PAGE result.
-