FGFR4 Protein (AA 22-369) (His tag)
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- Antigène Voir toutes FGFR4 Protéines
- FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 22-369
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Origine
- Macaque rhésus
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette FGFR4 protéine est marqué à la His tag.
- Fonction
- Rhesus macaque FGFR4 Protein
- Séquence
- Leu22-Asp369
- Attributs du produit
- Recombinant Rhesus macaque FGFR4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu22-Asp369.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product FGFR4 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))
- Autre désignation
- FGFR4 (FGFR4 Produits)
- Synonymes
- FGFR4 Protein, XFGFR-4 Protein, XFGFR-4a Protein, cd334 Protein, fgfr-4 Protein, jtk2 Protein, tkf Protein, xfgfr4 Protein, CD334 Protein, JTK2 Protein, TKF Protein, Fgfr-4 Protein, etID309818.21 Protein, wu:fc13h10 Protein, zgc:111935 Protein, fgfr-4c Protein, fgfr4 Protein, fibroblast growth factor receptor 4 Protein, fibroblast growth factor receptor 4 S homeolog Protein, FGFR4 Protein, fgfr4 Protein, Fgfr4 Protein, fgfr4.S Protein
- Sujet
- Fibroblast growth factor receptor 4 (FGF R4), also known as CD334, is a 110 kDa glycosylated transmembrane receptor tyrosine kinase.Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19.
- Poids moléculaire
- 39.66 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- XP_028705775
- Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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