Recombinant Human FGL1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Asp64-Asn305.
Pureté
> 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
Stérilité
0.22 μm filtered
niveau d'endotoxine
Less than 1EU per μg by the LAL method.
Biological Activity Comment
Immobilized Human LAG3, His Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Human FGL1, hFc Tag with the EC50 of 2.3μg/ml determined by ELISA. See testing image for detail.
FGL1
Origine: Cynomolgus
Hôte: Human Cells
Recombinant
>95 % as determined by reducing SDS-PAGE.
Restrictions
For Research Use only
Format
Liquid
Buffer
Supplied as 0.22μm filtered solution in 20 mM PB, 250 mM NaCl ( pH 7.4).
Stock
-80 °C
Stockage commentaire
Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Sujet
Fibrinogen-like protein 1 (FGL-1) is a protein that is structurally related to fibrinogen. In humans, FLG-1 is encoded by the FGL1 gene.Fibrinogen-like protein 1 is a member of the fibrinogen family of proteins, which also includes fibrinogen, fibrinogen-like protein 2, and clotting factors V, VIII, and XIII.Fibrinogen-like Protein 1 is a major immune inhibitory ligand of LAG-3.
Poids moléculaire
54.8 kDa. Due to glycosylation, the protein migrates to 60-66 kDa based on Tris-Bis PAGE result.