TNFRSF18 Protein (AA 22-153) (His tag)
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- Antigène Voir toutes TNFRSF18 Protéines
- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 22-153
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Origine
- Souris
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette TNFRSF18 protéine est marqué à la His tag.
- Fonction
- Mouse GITR/TNFRSF18 Protein
- Séquence
- Ser22-His153
- Attributs du produit
- Recombinant Mouse GITR/TNFRSF18 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser22-His153.
- Pureté
- > 95 % as determined by Tris-Bis PAGE
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product TNFRSF18 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
- Autre désignation
- GITR (TNFRSF18 Produits)
- Synonymes
- GITR Protein, TNFRSF18 Protein, AITR Protein, Gitr Protein, CD357 Protein, GITR-D Protein, TNF receptor superfamily member 18 Protein, tumor necrosis factor receptor superfamily, member 18 Protein, TNFRSF18 Protein, Tnfrsf18 Protein
- Sujet
- GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
- Poids moléculaire
- 15.2 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result.
- UniProt
- Q8C4K3
- Pathways
- Cancer Immune Checkpoints
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