Azurocidin Protein (AA 27-250) (His tag)

N° du produit ABIN7274790

Cette protéine Recombinant Azurocidin est produite dans HEK-293 Cells.

Aperçu rapide pour Azurocidin Protein (AA 27-250) (His tag) (ABIN7274790)

Antigène: Azurocidin (AZU1) (Azurocidin 1 (AZU1))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: HEK-293 Cells

Pureté: > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC

Détail du produit

Attributs du protein: AA 27-250

Purification/Conjugué: Cette Azurocidin protéine est marqué à la His tag.

Fonction: Human Azurocidin/CAP37/AZU1/HBP Protein

Séquence: Ile27-Pro250

Attributs du produit: Recombinant Human Azurocidin/CAP37/AZU1 /HBP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ile27-Pro250.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: Human Azurocidin on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Human Azurocidin is greater than 95% as determined by SEC-HPLC.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

Buffer: Lyophilized from 0.22 μm filtered solution in 20 mM PB, 500 mM NaCl ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Azurocidin (AZU1) (Azurocidin 1 (AZU1))

Autre désignation: Azurocidin

Sujet: Heparin-binding protein (HBP), also known as cationic antimicrobial protein 37 (CAP37) and Azurocidin, is a member of the serine protease family that includes Cathepsin G, neutrophil elastase (NE), and proteinase 3 (PR3). This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria, this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

Poids moléculaire: 25.3 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.

UniProt: P20160