IL31RA Protein (AA 20-519) (Fc Tag)
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- Antigène Voir toutes IL31RA Protéines
- IL31RA (Interleukin 31 Receptor A (IL31RA))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 20-519
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette IL31RA protéine est marqué à la Fc Tag.
- Fonction
- Human IL-31 RA Protein
- Séquence
- Ala20-Glu519
- Attributs du produit
- Recombinant Human IL-31 RA Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ala20-Glu519.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human IL-31, His Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Human IL-31 RA, hFc Tag with the EC50 of 1.2μg/ml determined by ELISA. The affinity constant of 1.5nM as determined in SPR assay (Biacore T200). See testing image for detail.
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- Discover our top product IL31RA Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- IL31RA (Interleukin 31 Receptor A (IL31RA))
- Autre désignation
- IL-31 RA (IL31RA Produits)
- Synonymes
- IL31RA Protein, CRL Protein, CRL3 Protein, GLM-R Protein, GLMR Protein, GPL Protein, IL-31RA Protein, PLCA2 Protein, PRO21384 Protein, hGLM-R Protein, Glmr Protein, NR10 Protein, interleukin 31 receptor A Protein, IL31RA Protein, Il31ra Protein
- Sujet
- Interleukin-31 receptor A (IL-31RA) is a newly identified type I cytokine receptor, that is related to gp130, the common receptor of the interleukin (IL) -6 family cytokines. IL-31RA forms a functional receptor complex for IL-31 together with the beta subunit of oncostatin M receptor (OSMRbeta). OSMRbeta is expressed in a subset of small-sized nociceptive neurons of adult dorsal root ganglia (DRGs).IL-31 and OSM may thus have redundant functions in the development of OSMRbeta-expressing neurons.
- Poids moléculaire
- 83.8 kDa. Due to glycosylation, the protein migrates to 110-135 kDa based on Tris-Bis PAGE result.
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