PAD4 (PADI4)
(Peptidyl Arginine Deiminase, Type IV (PADI4))
Type de proteíne
Recombinant
Attributs du protein
AA 1-663
Origine
Cynomolgus
Source
Escherichia coli (E. coli)
Purification/Conjugué
Cette PAD4 protéine est marqué à la His tag,Biotin.
Fonction
Biotinylated Cynomolgus PADI4 Protein (Primary Amine Labeling)
Séquence
Met1-Pro663
Attributs du produit
Recombinant Biotinylated Cynomolgus PADI4 Protein (Primary Amine Labeling) is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Pro663.
Supplied as 0.22μm filtered solution in 20 mM Tris, 500 mM NaCl, 10 % Glycerol, 0.5 mM TCEP, 1 mM EDTA ( pH 8.0).
Agent conservateur
Other preservative
Stock
-80 °C
Stockage commentaire
Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Date de péremption
12 months
Antigène
PAD4 (PADI4)
(Peptidyl Arginine Deiminase, Type IV (PADI4))
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Sujet
Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes.