PD-L1 Protein (AA 19-237) (Fc Tag)
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- Antigène Voir toutes PD-L1 Protéines
- PD-L1 (CD274 (PD-L1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 19-237
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Origine
- Souris
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette PD-L1 protéine est marqué à la Fc Tag.
- Fonction
- Mouse PD-L1/B7-H1 Protein
- Séquence
- Phe19-Arg237
- Attributs du produit
- Recombinant Mouse PD-L1/B7-H1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Phe19-Arg237.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 0.35 μM as determined in SPR assay (Biacore T200). See testing image for detail.
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- Discover our top product PD-L1 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- PD-L1 (CD274 (PD-L1))
- Autre désignation
- PD-L1 (PD-L1 Produits)
- Synonymes
- B7-H Protein, B7H1 Protein, PD-L1 Protein, PDCD1L1 Protein, PDCD1LG1 Protein, PDL1 Protein, A530045L16Rik Protein, B7h1 Protein, Pdcd1l1 Protein, Pdcd1lg1 Protein, Pdl1 Protein, RGD1566211 Protein, CD274 molecule Protein, CD274 antigen Protein, programmed cell death 1 ligand 2 Protein, CD274 Protein, Cd274 Protein, PDCD1LG2 Protein
- Sujet
- B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance.
- Poids moléculaire
- 51.5 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- NP_068693
- Pathways
- Cancer Immune Checkpoints
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