PDGFRA Protein (AA 24-524) (His tag)

N° du produit ABIN7275438

Détail du produit

Antigène: PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

Type de proteíne: Recombinant

Attributs du protein: AA 24-524

Origine: Cynomolgus

Source: HEK-293 Cells

Purification/Conjugué: Cette PDGFRA protéine est marqué à la His tag.

Fonction: Cynomolgus PDGF R alpha/PDGFRA Protein

Séquence: Gln24-Glu524

Attributs du produit: Recombinant Cynomolgus PDGF R alpha/PDGFRA Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln24-Glu524.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

Autre désignation: PDGF R alpha (PDGFRA Produits)

Synonymes: AI115593 Protein, CD140a Protein, Pdgfr-2 Protein, APDGFR Protein, PDGFACE Protein, CD140A Protein, PDGFR-2 Protein, PDGFR2 Protein, RHEPDGFRA Protein, PDGFR Protein, PDGFR-A Protein, platelet derived growth factor receptor alpha Protein, platelet derived growth factor receptor, alpha polypeptide Protein, platelet-derived growth factor receptor, alpha polypeptide L homeolog Protein, platelet-derived growth factor receptor, alpha polypeptide Protein, PDGFRA Protein, Pdgfra Protein, pdgfra.L Protein

Sujet: Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF.

Poids moléculaire: 57.32 kDa. Due to glycosylation, the protein migrates to 70-85 kDa based on Tris-Bis PAGE result.

UniProt: Q0PW86

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling