TNFRSF10C
Origine: Humain
Hôte: Human Cells
Recombinant
Greater than 95 % as determined by reducing SDS-PAGE.
SDS, WB, ELISA, MS
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
Buffer
Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
Stock
-20 °C,-80 °C
Stockage commentaire
-20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Date de péremption
12 months
Antigène
DcR1 (TNFRSF10C)
(Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
CD263 Protein, DCR1 Protein, DCR1-TNFR Protein, LIT Protein, TRAIL-R3 Protein, TRAILR3 Protein, TRID Protein, TNFRSF10C Protein, TNF receptor superfamily member 10c Protein, TNFRSF10C Protein
Sujet
The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the TNF family, which mediates apoptosis by the extrinsic pathway. Up-regulation of decoy receptors, DcR1 and DcR2, may result in diminished binding of TRAIL to their functional receptors. DcR1 expression occurs in a subset of EC and may contribute to resistance to TRAIL-induced apoptosis.
Poids moléculaire
23.5 kDa. Due to glycosylation, the protein migrates to 60-80 kDa based on Tris-Bis PAGE result.