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GLP1R Protein (Biotin,His-Avi Tag)

GLP1R Origine: Humain Hôte: HEK-293 Cells Recombinant 90,00 %
N° du produit ABIN7316843
  • Antigène Voir toutes GLP1R Protéines
    GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))
    Type de proteíne
    Recombinant
    Origine
    • 7
    • 2
    • 1
    Humain
    Source
    • 5
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette GLP1R protéine est marqué à la Biotin,His-Avi Tag.
    Fonction
    Biotinylated Human GLP1R Protein, His,Avitag™
    Séquence
    Ala 21 - Glu 139
    Attributs du produit
    Biotinylated Human GLP1R, His,Avitag is expressed from human 293 cells (HEK293). It contains AA Ala 21 - Glu 139 (Accession # P43220-1).
    Pureté
    90,00 %
    niveau d'endotoxine
    1.0 EU per μg
    Top Product
    Discover our top product GLP1R Protéine
  • Commentaires

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 17.3 kDa. The protein migrates as 30-34 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Stock
    -20 °C
    Stockage commentaire
    -20°C
  • Antigène
    GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))
    Autre désignation
    GLP1R (GLP1R Produits)
    Synonymes
    GLP1R Protein, LOC100228311 Protein, GLP-1R Protein, GLP1Rc Protein, Glip Protein, RATGL1RCP Protein, glucagon like peptide 1 receptor Protein, glucagon-like peptide 1 receptor Protein, GLP1R Protein, Glp1r Protein
    Sujet
    Synonyms:GLP-1, GLP-1-R, GLP-1R, glucagon like peptide 1 receptor,Description:This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke.
    Poids moléculaire
    17.3 kDa
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, cAMP Metabolic Process, Feeding Behaviour
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