IL-24 Protein (His tag)

N° du produit ABIN7448047

Détail du produit

Antigène: IL-24 (IL24) (Interleukin 24 (IL24))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette IL-24 protéine est marqué à la His tag.

Fonction: Human IL-24 Protein, His Tag (BLI verified)

Séquence: Gln 52 - Leu 206

Attributs du produit: Human IL-24 Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Gln 52 - Leu 206 (Accession # Q13007-1).

Pureté: 90,00 %

niveau d'endotoxine: 1.0 EU per μg

Classe de qualité: BLI verified

Information d'application

Commentaires:

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 20.0 kDa. The protein migrates as 30-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: IL-24 (IL24) (Interleukin 24 (IL24))

Autre désignation: IL-24 (IL24 Produits)

Synonymes: C49A Protein, FISP Protein, IL10B Protein, MDA7 Protein, MOB5 Protein, ST16 Protein, Mda7 Protein, St16 Protein, Mda-7 Protein, IL24 Protein, interleukin 24 Protein, IL24 Protein, Il24 Protein

Sujet: Synonyms:Interleukin-24,IL-24,Melanoma differentiation-associated gene 7 protein,MDA-7,Suppression of tumorigenicity 16 protein,IL24,MDA7,ST16,Description:Interleukin-24 (IL-24, also known as melanoma differentiation-associated gene-7) belongs to the family of IL-10-related cytokines, which includes IL-10, -19, -20, -22, -24 and -26. Interleukin 24 signals through two heterodimeric receptors: IL-20R1/IL-20R2 and IL-22R1/IL-20R2. Upon binding to its receptors, IL-24 induces rapid activation of Stat-1 and Stat-3 transcription factors, which appear to play a role in cell survival and proliferation . Structurally and functionally, IL-24 is highly conserved across species.IL-24 has been shown to possess cancer-specific apoptosis-inducing activity, and has therefore been suggested as a potential anti-cancer agent.

Poids moléculaire: 20.0 kDa

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy