IL12RB1 Protein (Biotin,His-Avi Tag)

N° du produit ABIN7447938

Détail du produit

Antigène: IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette IL12RB1 protéine est marqué à la Biotin,His-Avi Tag.

Fonction: Biotinylated Human IL-12 R beta 1 / CD212 Protein, His,Avitag™ (MALS verified)

Séquence: Cys 24 - Glu 540

Attributs du produit: Biotinylated Human IL-12 R beta 1, His,Avitag is expressed from human 293 cells (HEK293). It contains AA Cys 24 - Glu 540 (Accession # P42701-1).

Pureté: 95,00 %

niveau d'endotoxine: 1.0 EU per μg

Classe de qualité: MALS verified

Information d'application

Commentaires:

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 60.7 kDa. The protein migrates as 70-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))

Autre désignation: IL-12 R beta 1 (IL12RB1 Produits)

Synonymes: Il12rb Protein, IL12RB1 Protein, IL-12R Protein, CD212 Protein, IL-12R-BETA1 Protein, IL12RB Protein, IL-12R[b] Protein, interleukin 12 receptor subunit beta 1 Protein, interleukin 12 receptor, beta 1 Protein, Il12rb1 Protein, IL12RB1 Protein

Sujet: Synonyms:IL-12 R beta 1,IL12RB1,CD212,IL12R,IL12RB,IL-12RB1,Description:The human IL-12 R subunit is a member of the cytokine receptor superfamily and the functional high-affinity IL-12R is composed of at least two beta-type cytokine receptor subunits, each independently exhibiting a low affinity for IL-12. IL-12 R beta 1 (Interleukin-12 receptor subunit beta-1) is also known as IL-12RB1, CD212. Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.

Poids moléculaire: 60.7 kDa

NCBI Accession: NP_005526

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation