MADCAM1 Protein (Biotin,Fc-Avi Tag)
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- Antigène Voir toutes MADCAM1 Protéines
- MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette MADCAM1 protéine est marqué à la Biotin,Fc-Avi Tag.
- Fonction
- Biotinylated Human MAdCAM-1 Protein, Fc,Avitag™ (MALS verified)
- Séquence
- Gln 19- Gln 333
- Attributs du produit
- Biotinylated Human MAdCAM-1, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Gln 19- Gln 333 (Accession # Q4PKD0-1).
- Pureté
- 95,00 %
- niveau d'endotoxine
- 1.0 EU per μg
- Classe de qualité
- MALS verified
- Top Product
- Discover our top product MADCAM1 Protéine
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- Commentaires
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This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 63 kDa. The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Stock
- -20 °C
- Stockage commentaire
- -20°C
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- Antigène
- MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
- Autre désignation
- MAdCAM-1 (MADCAM1 Produits)
- Synonymes
- MACAM1 Protein, AV211525 Protein, mucosal vascular addressin cell adhesion molecule 1 Protein, MADCAM1 Protein, Madcam1 Protein
- Sujet
- Synonyms:MAdCAM-1,Mucosal vascular addressin cell adhesion molecule 1 transcript variant 1,Description:The mucosal addressin cell adhesion molecule-1 (MAdCAM-1) takes a key role in the endothelial adhesion and migration of lymphocytes to sites of inflammation in inflammatory disease. In vitro and in vivo data indicate that blockade of the adhesion molecule mucosal address in cell adhesion molecule (MAdCAM) pathway decreases leukocyte homing to the gut by inhibiting the interaction between MAdCAM and its ligand the α4β7 integrin expressed on lymphocytes.
- Poids moléculaire
- 63 kDa
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