CDCP1 Protein (AA 30-368) (His tag)

N° du produit ABIN7454247

Détail du produit

Antigène: CDCP1 (CUB Domain Containing Protein 1 (CDCP1))

Type de proteíne: Recombinant

Attributs du protein: AA 30-368

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CDCP1 protéine est marqué à la His tag.

Fonction: Human CDCP1 (30-368) Protein

Séquence: Phe30-Arg368

Attributs du produit: Recombinant Human CDCP1 (30-368) Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe30-Arg368.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human CDCP1 (30-368) , His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Anti-CDCP1 Antibody, hFc Tag with the EC50 of 13.2ng/ml determined by ELISA. See testing image for detail.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in 20 mM PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: CDCP1 (CUB Domain Containing Protein 1 (CDCP1))

Autre désignation: CDCP1 (CDCP1 Produits)

Synonymes: CD318 Protein, SIMA135 Protein, TRASK Protein, 9030022E12Rik Protein, AA409659 Protein, E030027H19Rik Protein, RGD1305578 Protein, zgc:113071 Protein, CUB domain containing protein 1 Protein, CUB domain containing protein 1a Protein, CDCP1 Protein, Cdcp1 Protein, cdcp1a Protein

Sujet: Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression.

Poids moléculaire: 39.03 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.