Amphiregulin Protein (AREG) (AA 20-187) (Fc Tag)

N° du produit ABIN7491191

Détail du produit

Antigène: Amphiregulin (AREG)

Type de proteíne: Recombinant

Attributs du protein: AA 20-187

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Amphiregulin protéine est marqué à la Fc Tag.

Fonction: Recombinant human AREG protein with C-terminal human Fc tag

Specificité: AREG (Ser20-Lys187) hFc (Glu99-Ala330)

Attributs du produit: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: Amphiregulin (AREG)

Autre désignation: AREG (AREG Produits)

Synonymes: AR Protein, CRDGF Protein, SDGF Protein, Sdgf Protein, AREG Protein, AREGB Protein, AREG/SDGF Protein, amphiregulin Protein, AREG Protein, Areg Protein

Sujet: The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014]

Poids moléculaire: predicted molecular mass of 44.9 kDa after removal of the signal peptide. The apparent molecular mass of AREG-hFc is 53-70 kDa due to glycosylation.

UniProt: P15514

Pathways: Signalisation RTK, EGFR Signaling Pathway