MPXV A29L (AA 1-110) protein (His tag)

N° du produit ABIN7491237

Détail du produit

Antigène: MPXV A29L

Type de proteíne: Recombinant

Attributs du protein: AA 1-110

Origine: Mpox Virus

Source: HEK-293 Cells

Purification/Conjugué: His tag

Fonction: Recombinant Monkeypox virus A29L Protein with C-terminal 6xHis tag

Specificité: Monkeypox virus A29L (Met1-Glu110) 6xHis tag

Attributs du produit: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Pureté: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: MPXV A29L

Sujet: Monkeypox is a rare zoonosis caused by monkeypox virus, which has become the most serious orthpoxvirus and consists of complex double stranded DNA. The cases are mostly in central and western Africa. The pathogenesis of monkeypox is that the virus invades the body from respiratory mucosa, multiplies in lymphocytes, and incurs into blood producing transient venereal toxemia. after the virus multiplies in cells, the cells can invade the blood and propagate to the skin of the whole body, causing lesions. A29L binds to cell surface heparin to promote fusion of viral membrane with host plasma membrane.

Poids moléculaire: predicted molecular mass of 13.4 kDa after removal of the signal peptide. The apparent molecular mass of Monkeypox virus A29L-His is 10-25 kDa due to glycosylation.

UniProt: Q77HM6