Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Pro BDNF Protéine

proBDNF Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7455668
  • Antigène Tous les produits Pro BDNF (proBDNF)
    Pro BDNF (proBDNF) (Pro-Brain-Derived Neurotrophic Factor (proBDNF))
    Type de proteíne
    Recombinant
    Origine
    • 2
    • 1
    Humain
    Source
    • 3
    Escherichia coli (E. coli)
    Fonction
    Recombinant Human Pro-Brain-Derived Neurotrophic Factor is produced by our E.coli expression system and the target gene encoding Ala19-Arg247(R125A, R127A, R128A) is expressed.
    Attributs du produit
    Extracellular Domain Protein
    Purification
    Affinity purification
    Pureté
    Greater than 95 % as determined by reducing SDS-PAGE.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 8.0.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Date de péremption
    12 months
  • Antigène
    Pro BDNF (proBDNF) (Pro-Brain-Derived Neurotrophic Factor (proBDNF))
    Autre désignation
    pro-BDNF (proBDNF Produits)
    Sujet
    The precursor form of Brain-Derived Neurotrophic Factor (pro-BDNF) interacts preferentially with the pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin and induces neuronal apoptosis, whereas mature BDNF selectively binds with high affinity to the TrkB kinase receptor and promotes the survival, growth and differentiation of neurons. As proneurotrophins and mature neurotrophins elicit opposite biological effects, Pro-BDNF cleavage in the neuronal system is regulated in a specific and cell-context dependent manner. Pro-BDNF plays important role in negative regulation of neurotrophic actions in the brain.
    Poids moléculaire
    25.6 KDa
    UniProt
    P23560
Vous êtes ici:
Support technique