IL28A Protein (His tag)
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- Antigène Voir toutes IL28A Protéines
- IL28A (Interleukin 28A (Interferon, lambda 2) (IL28A))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette IL28A protéine est marqué à la His tag.
- Fonction
- Recombinant Human Interferon Lambda-2 is produced by our Mammalian expression system and the target gene encoding Val26-Val200 is expressed with a 6His tag at the C-terminus.
- Attributs du produit
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Pureté
- Greater than 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product IL28A Protéine
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Interleukin 28A (Interferon, lambda 2) (IL28A) (Active) protein
IL28A Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 28A (Interferon, lambda 2) (IL28A) (AA 26-200) protein (His tag)IL28A Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Date de péremption
- 12 months
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- Antigène
- IL28A (Interleukin 28A (Interferon, lambda 2) (IL28A))
- Autre désignation
- IL-28A (IL28A Produits)
- Synonymes
- EG330496 Protein, IL-28A Protein, Il28a Protein, IL28A Protein, interferon lambda 2 Protein, Ifnl2 Protein, IFNL2 Protein
- Sujet
- IL-28A (Interferon-λ2? IFN-λ2), IL-28B/IFN-λ3, and IL-29/IFN-λ1 are type III interferons which are distantly related to IL-10 family and type I IFN family cytokines. Mature human IL-28A is an approximately 22-25 kDa protein that shares 66 % amino acid (aa) sequence identity with mouse and rat IL-28A and shows cross-species activity. It shares 96 % and 70 % aa sequence identity with human IL-28B and IL-29, respectively. IL-28A promotes the Th1 polarization of dendritic cells in the airway and inhibits Th2 and Th17 mediated inflammation. IL-28A additionally exhibits anti-tumor activity, in part by enhancing IL-12 dependent anti-tumor CTL responses in vivo. In contrast, it is up-regulated in invasive bladder cancer where it promotes tumor cell migration.
- Poids moléculaire
- 20.6 KDa
- UniProt
- Q8IZJ0
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