CD14 Protein (CD14) (AA 20-352) (His tag)

N° du produit ABIN7491389

Détail du produit

Antigène: CD14

Type de proteíne: Recombinant

Attributs du protein: AA 20-352

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CD14 protéine est marqué à la His tag.

Fonction: Recombinant Human CD14(20-352) Protein with C-terminal 7xHis tag

Specificité: CD14 (Thr20-Cys352) 7xHis tag

Attributs du produit: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Pureté: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: CD14

Autre désignation: CD14 (CD14 Produits)

Synonymes: CD14 molecule Protein, CD14 antigen Protein, CD14 Protein, Cd14 Protein

Sujet: The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2020]

Poids moléculaire: predicted molecular mass of 36.7 kDa after removal of the signal peptide. The apparent molecular mass of CD14(20-352)-7xHis is 35-55 kDa due to glycosylation.

UniProt: P08571

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades