Osteoactivin Protein (GPNMB) (AA 23-496) (His tag)

N° du produit ABIN7491429

Détail du produit

Antigène: Osteoactivin (GPNMB)

Type de proteíne: Recombinant

Attributs du protein: AA 23-496

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Osteoactivin protéine est marqué à la His tag.

Fonction: Recombinant Human GPNMB Protein with C-terminal 6xHis tag

Specificité: GPNMB (Lys23-Met496) 6xHis tag

Attributs du produit: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Pureté: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: Osteoactivin (GPNMB)

Autre désignation: GPNMB (GPNMB Produits)

Synonymes: HGFIN Protein, NMB Protein, DC-HIL Protein, Dchil Protein, ipd Protein, glycoprotein nmb Protein, glycoprotein (transmembrane) nmb Protein, glycoprotein nmb L homeolog Protein, Gpnmb Protein, GPNMB Protein, gpnmb.L Protein

Sujet: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Poids moléculaire: predicted molecular mass of 53.9 kDa after removal of the signal peptide. The apparent molecular mass of GPNMB-His is 70-130 kDa due to glycosylation.

UniProt: Q14956