GRPR Protein (AA 1-38) (Fc Tag)

N° du produit ABIN7491457

Détail du produit

Antigène: GRPR (Gastrin-Releasing Peptide Receptor (GRPR))

Type de proteíne: Recombinant

Attributs du protein: AA 1-38

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette GRPR protéine est marqué à la Fc Tag.

Fonction: Recombinant Human GRPR Protein with C-terminal human Fc tag

Specificité: GRPR (Met1-Gly38) hFc (Glu99-Ala330)

Attributs du produit: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: GRPR (Gastrin-Releasing Peptide Receptor (GRPR))

Autre désignation: GRPR (GRPR Produits)

Synonymes: GRPR Protein, GRP-R Protein, gastrin releasing peptide receptor Protein, GRPR Protein, Grpr Protein

Sujet: Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008]

Poids moléculaire: predicted molecular mass of 30.4 kDa after removal of the signal peptide. The apparent molecular mass of GRPR-hFc is 35-55 kDa due to glycosylation.

UniProt: P30550