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STEAP2 Protéine

STEAP2 Origine: Humain Hôte: HEK-293 Cells Synthetic Nanodisc
N° du produit ABIN7491745
  • Antigène Voir toutes STEAP2 Protéines
    STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))
    Type de proteíne
    Synthetic Nanodisc
    Origine
    • 4
    • 1
    Humain
    Source
    • 2
    • 2
    • 1
    HEK-293 Cells
    Fonction
    Human STEAP2 full length protein-synthetic nanodisc
    Attributs du produit
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • Commentaires

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Date de péremption
    12 months
  • Antigène
    STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))
    Autre désignation
    STEAP2 (STEAP2 Produits)
    Synonymes
    4921538B17Rik Protein, AI930049 Protein, AW045895 Protein, IPCA-1 Protein, IPCA1 Protein, PCANAP1 Protein, STAMP1 Protein, STMP Protein, PUMPCn Protein, six transmembrane epithelial antigen of prostate 2 Protein, STEAP2 metalloreductase Protein, Steap2 Protein, STEAP2 Protein
    Sujet
    A member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Poids moléculaire
    The human full length STEAP2 protein has a MW of 56.1 kDa
    UniProt
    Q8NFT2
    Pathways
    Transition Metal Ion Homeostasis
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