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ESYT1 Protéine

ESYT1 Origine: Humain Hôte: HEK-293 Cells Synthetic Nanodisc
N° du produit ABIN7491635
  • Antigène Tous les produits ESYT1
    ESYT1 (Extended Synaptotagmin-Like Protein 1 (ESYT1))
    Type de proteíne
    Synthetic Nanodisc
    Origine
    • 2
    • 1
    Humain
    Source
    • 2
    • 1
    HEK-293 Cells
    Fonction
    Human ESYT1 full length protein-synthetic nanodisc
    Attributs du produit
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • Commentaires

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Date de péremption
    12 months
  • Antigène
    ESYT1 (Extended Synaptotagmin-Like Protein 1 (ESYT1))
    Autre désignation
    ESYT1 (ESYT1 Produits)
    Synonymes
    FAM62A Protein, fam62a Protein, si:ch211-239j9.4 Protein, DKFZp459I1628 Protein, MBC2 Protein, Fam62a Protein, Mbc2 Protein, vp115 Protein, extended synaptotagmin 1 Protein, extended synaptotagmin-like protein 1b Protein, extended synaptotagmin-like protein 1 Protein, ESYT1 Protein, esyt1b Protein, Esyt1 Protein
    Sujet
    Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. Helps tether the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane.[UniProtKB/Swiss-Prot Function]
    Poids moléculaire
    The human full length ESYT1 protein has a MW of 122.9 kDa
    UniProt
    Q9BSJ8
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