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C5AR1 Protéine

C5AR1 Origine: Humain Hôte: HEK-293 Cells Synthetic Nanodisc
N° du produit ABIN7491549
  • Antigène Voir toutes C5AR1 Protéines
    C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
    Type de proteíne
    Synthetic Nanodisc
    Origine
    • 6
    • 3
    Humain
    Source
    • 3
    • 2
    • 2
    • 2
    HEK-293 Cells
    Fonction
    Human C5AR1 full length protein-synthetic nanodisc
    Attributs du produit
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • Commentaires

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Date de péremption
    12 months
  • Antigène
    C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
    Autre désignation
    C5AR1 (C5AR1 Produits)
    Synonymes
    C5A Protein, C5AR Protein, C5R1 Protein, CD88 Protein, C5aR Protein, C5r1 Protein, Cd88 Protein, D7Msu1 Protein, GPR77 Protein, complement C5a receptor 1 Protein, complement component 5a receptor 1 Protein, C5AR1 Protein, C5ar1 Protein, c5ar1 Protein
    Sujet
    Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production
    Poids moléculaire
    The human full length C5AR1 protein has a MW of 39.3 kDa
    UniProt
    P21730
    Pathways
    Système du Complément
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