Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

CXCR7 Protéine

CXCR7 Origine: Humain Hôte: HEK-293 Cells Synthetic Nanodisc
N° du produit ABIN7491631
  • Antigène Voir toutes CXCR7 Protéines
    CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))
    Type de proteíne
    Synthetic Nanodisc
    Origine
    • 6
    • 2
    • 1
    Humain
    Source
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Fonction
    Human CXCR7 full length protein-synthetic nanodisc
    Attributs du produit
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • Commentaires

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Date de péremption
    12 months
  • Antigène
    CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))
    Autre désignation
    ACKR3 (CXCR7 Produits)
    Synonymes
    CMKOR1 Protein, CXC-R7 Protein, CXCR-7 Protein, CXCR7 Protein, GPR159 Protein, RDC-1 Protein, RDC1 Protein, AW541270 Protein, Cmkor1 Protein, Cxcr7 Protein, Rdc1 Protein, ackr3 Protein, cxcr7 Protein, rdc1 Protein, xcxcr7 Protein, atypical chemokine receptor 3 Protein, ORF 74; similar to Kaposi's sarcoma-associated herpesvirus ORF 74 Protein, atypical chemokine receptor 3 L homeolog Protein, ACKR3 Protein, MmrVgp88 Protein, Ackr3 Protein, ackr3.L Protein
    Sujet
    A member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.
    Poids moléculaire
    The human full length CXCR7 protein has a MW of 41.5 kDa
    UniProt
    P25106
    Pathways
    Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling
Vous êtes ici:
Support technique