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TMCC3 Protéine

TMCC3 Origine: Humain Hôte: HEK-293 Cells Synthetic Nanodisc
N° du produit ABIN7491749
  • Antigène Tous les produits TMCC3
    TMCC3 (Transmembrane and Coiled-Coil Domain Family 3 (TMCC3))
    Type de proteíne
    Synthetic Nanodisc
    Origine
    • 1
    • 1
    Humain
    Source
    • 2
    HEK-293 Cells
    Fonction
    Human TMCC3 full length protein-synthetic nanodisc
    Attributs du produit
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • Commentaires

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Date de péremption
    12 months
  • Antigène
    TMCC3 (Transmembrane and Coiled-Coil Domain Family 3 (TMCC3))
    Autre désignation
    TMCC3 (TMCC3 Produits)
    Synonymes
    wu:fb81d10 Protein, wu:fb83h01 Protein, wu:fk68a09 Protein, wu:fl22e07 Protein, si:dkey-183c16.4 Protein, DKFZp469H0211 Protein, AW488095 Protein, C630016B22Rik Protein, C88213 Protein, Tmcc1 Protein, RGD1307241 Protein, transmembrane and coiled-coil domain family 3 Protein, transmembrane and coiled coil domains 3 Protein, tmcc3 Protein, TMCC3 Protein, Tmcc3 Protein
    Sujet
    This protein belongs to the the transmembrane and coiled-coil domain (TMCC) family, which shares common structural motifs (two transmembrane domains and two coiled-coil domains). TMCC3 was isolated as a novel gene isolated from human brain, and later became known as a novel gene up-regulated in the developing brain, especially in the ventral tegmentum. There is no resolved structure or defined function.
    Poids moléculaire
    The human full length TMCC3 protein has a MW of 53.8 kDa
    UniProt
    Q9ULS5
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