TMEM180 Protéine

N° du produit ABIN7491697

Détail du produit

Antigène: TMEM180 (Transmembrane Protein 180 (TMEM180))

Type de proteíne: Synthetic Nanodisc

Origine: Humain

Source: HEK-293 Cells

Fonction: Human MFSD13A full length protein-synthetic nanodisc

Attributs du produit: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Information d'application

Commentaires:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: TMEM180 (Transmembrane Protein 180 (TMEM180))

Autre désignation: MFSD13A (TMEM180 Produits)

Synonymes: C10orf77 Protein, bA18I14.8 Protein, 4930449A08Rik Protein, 4930538D17Rik Protein, major facilitator superfamily domain containing 13A Protein, major facilitator superfamily domain containing 13a Protein, MFSD13A Protein, Mfsd13a Protein

Sujet: MFSD13A, also called Transmembrane protein 180 (TMEM180), is a transmembrane protein that belongs to the glycoside-pentoside-hexuronide (GPH):cation symporter family. Members of this family catalyze symport of a sugar molecule with a monovalent cation (H or Na ). MFSD13A is classified as a member of the cation symporter family and a multi-pass membrane protein, but little information is available regarding its substrate and topology.

Poids moléculaire: The human full length MFSD13A protein has a MW of 57.4 kDa

UniProt: Q14CX5