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G Protein-Coupled Receptor 133 Protein (GPR133)

GPR133 Origine: Humain Hôte: HEK-293 Cells Synthetic Nanodisc
N° du produit ABIN7491529
  • Antigène Voir toutes G Protein-Coupled Receptor 133 (GPR133) Protéines
    G Protein-Coupled Receptor 133 (GPR133)
    Type de proteíne
    Synthetic Nanodisc
    Origine
    Humain
    Source
    • 1
    HEK-293 Cells
    Fonction
    Human ADGRD1 full length protein-synthetic nanodisc
    Attributs du produit
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • Commentaires

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Date de péremption
    12 months
  • Antigène
    G Protein-Coupled Receptor 133 (GPR133)
    Autre désignation
    ADGRD1 (GPR133 Produits)
    Synonymes
    GPR133 Protein, zgc:103546 Protein, PGR25 Protein, E230012M21Rik Protein, adhesion G protein-coupled receptor D1 Protein, ADGRD1 Protein, adgrd1 Protein, Adgrd1 Protein
    Sujet
    The adhesion G-protein-coupled receptors (GPCRs), including GPR133, are membrane-bound proteins with long N termini containing multiple domains. GPCRs, or GPRs, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.
    Poids moléculaire
    The human full length ADGRD1 protein has a MW of 96.5 kDa
    UniProt
    Q6QNK2
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