Claudin 9 Protein-VLP (CLDN9)
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- Antigène Voir toutes Claudin 9 (CLDN9) Protéines
- Claudin 9 (CLDN9)
- Type de proteíne
- VLP
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Origine
- Humain
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Source
- HEK-293 Cells
- Fonction
- Human Claudin-9 / CLDN9 Full Length Protein (VLP)
- Séquence
- Met 1 -Val 217
- Attributs du produit
- Human Claudin-9 Full Length Protein-VLP is expressed from human 293 cells (HEK293). It contains AA Met 1 -Val 217 (Accession # O95484-1).
- niveau d'endotoxine
- 1.0 EU per μg
- Top Product
- Discover our top product CLDN9 Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, Arginine, pH 7.4
- Stock
- -80 °C
- Stockage commentaire
- -70°C
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- Antigène
- Claudin 9 (CLDN9)
- Autre désignation
- Claudin-9 (CLDN9 Produits)
- Synonymes
- CLDN9 Protein, nmf329 Protein, claudin 9 Protein, CLDN9 Protein, Cldn9 Protein
- Sujet
- Claudin-9 belongs to the claudin family. Claudins constitute integral membrane proteins responsible for solute and electrolyte permeability of the tight junction that serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Tight junctions also play a critical role in maintaining cell polarity and signal transductions. Claudin-9 creates charge specific channels in the paracellular space, plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity, is required to preserve sensory cells in the hearing organ because claudin-9-defective tight junctions fail to shield the basolateral side of hair cells from the K+-rich endolymph. Its ion barrier function is essential in the cochlea, but appears to be dispensable in other organs. Is one of the entry cofactors for hepatitis C virus, it enables HCV entry into target cells just as efficiently as CLDN1.
- Pathways
- Cell-Cell Junction Organization, Hepatitis C
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