NKG2A & CD94 protein (mFc Tag)

N° du produit ABIN7488870

Détail du produit

Antigène: NKG2A & CD94

Type de proteíne: Recombinant

Origine: Rat

Source: HEK-293 Cells

Purification/Conjugué: mFc Tag

Fonction: Rat NKG2A&CD94 Protein, Mouse IgG2a Fc Tag (MALS verified)

Séquence: Thr 90 - Asn 231 (NKG2A) & Lys 32 - Thr 179 (CD94)

Attributs du produit: Rat NKG2A&CD94 Protein, Mouse IgG2a Fc Tag is expressed from human 293 cells (HEK293). It contains AA Thr 90 - Asn 231 (NKG2A) & Lys 32 - Thr 179 (CD94) (Accession # O54872-1(NKG2A) & O35778-1(CD94).

Pureté: 95 %

niveau d'endotoxine: 1.0 EU per μg

Classe de qualité: MALS verified

Information d'application

Commentaires:

This protein carries a mouse IgG2a Fc tag at the C-terminus. (mFc(mIgG2a) The protein has a calculated MW of 61.0 kDa. The protein migrates as 67-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: NKG2A & CD94

Autre désignation: NKG2A&CD94

Sujet: CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 Molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.

Poids moléculaire: 61.0 kDa